Modelling Proteasome Dynamics in a Bayesian Framework - Sabine Stübler
-40% ar kodu BOOKS
Piegāde 10-16 darba dienu laikā
30 dienu atgriešanas politika
Sabine Stübler compares different proteasome isoforms and subtypes in terms of their transport and active site-related parameters applying an existing computational model. In a second step, the author extends this model to be able to describe the influence of proteasome inhibitors in in vitro experiments. The computational model, which describes the hydrolysis of short fluorogenic peptides by the 20S protea ... Pilns apraksts
Jums varētu patikt arī
TOP
The Body Keeps the Score: Brain, Mind, and Body in the Healing of Trauma
-40% ar kodu BOOKS
Piegādātāja noliktavā
TOP
No Bad Parts: Healing Trauma and Restoring Wholeness with the Internal Family Systems Model
-40% ar kodu BOOKS
Nav noliktavā
TOP
Maybe You Should Talk to Someone: a therapist, her thearapist, and our lives revealed
-40% ar kodu BOOKS
Piegādātāja noliktavā
TOP
The Myth of Normal: Trauma, Illness, and Healing in a Toxic Culture
-40% ar kodu BOOKS
Noliktavā
TOP
Oxford Handbook of Clinical Medicine
Peter Hateley, Iain McGurgan, Ian B. Wilkinson, Tim Raine, Dearbhla Kelly, Kate Wiles
-40% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Harrison's Principles of Internal Medicine (Vol.1 & Vol.2)
Stephen Hauser, Joseph Loscalzo, Steven Holland, Dan Longo, J. Larry Jameson, Dennis Kasper, Carol Langford, Anthony Fauci
-40% ar kodu BOOKS
Piegādātāja noliktavā
TOP
The Checklist Manifesto: How to Get Things Right
-40% ar kodu BOOKS
Piegādātāja noliktavā
TOP
On Connection: 'Powerful' MATT HAIG
-40% ar kodu BOOKS
Piegādātāja noliktavā
TOP
How Not To Die: Discover the foods scientifically proven to prevent and reverse disease
-40% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Vademecum Metabolicum: Diagnosis and Treatment of Inborn Errors of Metabolism Forword by William L. Nyhan, San Diego, USA
Johannes Zschocke, Georg F. Hoffmann
-40% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Cellular and Molecular Immunology
Sarah Henrickson, Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai
-40% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Physics, Pharmacology and Physiology for Anaesthetists: Key Concepts for the FRCA
Matthew E. Cross, Emma V. E. Plunkett
-40% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Being Mortal: Medicine and What Matters in the End
-40% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Pocket Guide to Teaching for Clinical Instructors
-40% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Oxford Handbook of Critical Care
Andrew Webb, Mervyn Singer, Alice Carter
-40% ar kodu BOOKS
Piegādātāja noliktavā
TOP
The Wills Eye Manual: Print + eBook with Multimedia: Office and Emergency Room Diagnosis and Treatment of Eye Disease
-40% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Who Deserves Your Love: How to Create Boundaries to Start, Strengthen or End Any Relationship
-40% ar kodu BOOKS
Piegādātāja noliktavā
Aprašymas
Sabine Stübler compares different proteasome isoforms and subtypes in terms of their transport and active site-related parameters applying an existing computational model. In a second step, the author extends this model to be able to describe the influence of proteasome inhibitors in in vitro experiments. The computational model, which describes the hydrolysis of short fluorogenic peptides by the 20S proteasome, is calibrated to experimental data from different proteasome isoforms using an approximate Bayesian computation approach. The dynamics of proteasome inhibitors are included into the model in order to demonstrate how to modulate the inhibitor’s transport parameters for strong or isoform-specific inhibition.
Vairāk informācijas
| Autors | Sabine Stübler |
|---|---|
| Izdevējs | Springer Fachmedien Wiesbaden |
| Izlaides gads | 2017 |
| Vāka tips | Mīkstais vāks |
| EAN | 9783658201661 |