Humanized Mice -
-30% ar kodu BOOKS
Piegāde 17-23 darba dienu laikā
30 dienu atgriešanas politika
The term humanized mouse in this text refers to a mouse in which human tissues and cells have been transplanted and show the same biological function as they do in the human body. That is, the physiological properties and functions of tra- planted human tissues and cells can be analyzed in the mouse instead of using a living human body. It should therefore be possible to study the pathophysiology and treatm ... Pilns apraksts
Jums varētu patikt arī
TOP
The Myth of Normal: Trauma, Illness, and Healing in a Toxic Culture
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
The Body Keeps the Score: Brain, Mind, and Body in the Healing of Trauma
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
No Bad Parts: Healing Trauma and Restoring Wholeness with the Internal Family Systems Model
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
On Connection: 'Powerful' MATT HAIG
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Oxford Handbook of Clinical Medicine
Peter Hateley, Iain McGurgan, Ian B. Wilkinson, Tim Raine, Dearbhla Kelly, Kate Wiles
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Harrison's Principles of Internal Medicine (Vol.1 & Vol.2)
Stephen Hauser, Joseph Loscalzo, Steven Holland, Dan Longo, J. Larry Jameson, Dennis Kasper, Carol Langford, Anthony Fauci
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
The Checklist Manifesto: How to Get Things Right
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Maybe You Should Talk to Someone: a therapist, her thearapist, and our lives revealed
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
How Not To Die: Discover the foods scientifically proven to prevent and reverse disease
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Lifespan: Why We Age - and Why We Don't Have To
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Vademecum Metabolicum: Diagnosis and Treatment of Inborn Errors of Metabolism Forword by William L. Nyhan, San Diego, USA
Johannes Zschocke, Georg F. Hoffmann
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Cellular and Molecular Immunology
Sarah Henrickson, Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Physics, Pharmacology and Physiology for Anaesthetists: Key Concepts for the FRCA
Matthew E. Cross, Emma V. E. Plunkett
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Being Mortal: Medicine and What Matters in the End
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Pocket Guide to Teaching for Clinical Instructors
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Oxford Handbook of Critical Care
Andrew Webb, Mervyn Singer, Alice Carter
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
The Wills Eye Manual: Print + eBook with Multimedia: Office and Emergency Room Diagnosis and Treatment of Eye Disease
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Who Deserves Your Love: How to Create Boundaries to Start, Strengthen or End Any Relationship
-30% ar kodu BOOKS
Piegādātāja noliktavā
Aprašymas
The term humanized mouse in this text refers to a mouse in which human tissues and cells have been transplanted and show the same biological function as they do in the human body. That is, the physiological properties and functions of tra- planted human tissues and cells can be analyzed in the mouse instead of using a living human body. It should therefore be possible to study the pathophysiology and treatment of human diseases in mice with good reproducibility. Thus, the hum- ized mouse can be used as a potent tool in both basic and clinical research in the future. The development of appropriate immunodeficient mice has been indispensable in the creation of the humanized mouse, which has been achieved through many years of efforts by several laboratories. The first stage on the road to the humanized mouse was the report on nude mice by Isaacson and Cattanach in 1962. Thereafter, nude mice were studied in detail by Falanagan and, in 1968, Pantelouris found that these mice have no thymus gland, which suggested that the mice lack transplan- tion immunity against xenografts such as human hematopoietic stem cells. At the Nude Mouse Workshops (organized by Regard, Povlsen, Nomura and colleagues) that were held nine times between 1972 and 1997, the possibility of creating a humanized mouse using nude mice was extensively examined. The results, however, showed that certain human cancers can be engrafted in nude mice, but unfortunately engraftment of normal human tissue was almost impossible.
Vairāk informācijas
| Izdevējs | Springer Berlin Heidelberg |
|---|---|
| Series | Current Topics in Microbiology and Immunology |
| Izlaides gads | 2008 |
| Vāka tips | Cietais vāks |
| EAN | 9783540756460 |