Gene Function Analysis -
-30% ar kodu BOOKS
Piegāde 17-23 darba dienu laikā
30 dienu atgriešanas politika
This volume of Methods in Molecular Biology focuses on techniques to determine the function of a gene. Traditionally, the function of a gene was determined following cloning, which provided its DNA sequence and an ab- ity to modify this sequence. Experiments were performed that looked for p- notypic changes in a cell line or model organism following modifications to the sequence, knocking out of the gene, o ... Pilns apraksts
Jums varētu patikt arī
TOP
Six Not-so-easy Pieces: Einstein's Relativity, Symmetry, and Space-Time
Richard P. Feynman, Robert B. Leighton, Matthew Sands
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Six Easy Pieces: Essentials of Physics Explained by Its Most Brilliant Teacher
Richard P. Feynman, Robert B. Leighton, Matthew Sands
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Behave: The Biology of Humans at Our Best and Worst
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
The Age of Alchemy: How Early Innovators Shaped Modern Chemistry
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
The Secrets of our DNA: How Genetics has Changed the World
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Why We Sleep: Unlocking the Power of Sleep and Dreams
-30% ar kodu BOOKS
Noliktavā
TOP
Astrophysics for People in a Hurry: Essays on the Universe and Our Place Within It
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
The Rise and Fall of the Dinosaurs: A New History of a Lost World
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
The Rise and Reign of the Mammals: A New History, from the Shadow of the Dinosaurs to Us
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Determined: The Science of Life Without Free Will
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Learn Faster, Perform Better: A Musician's Guide to the Neuroscience of Practicing
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Beyond Inheritance: Our Ever-Mutating Cells and a New Understanding of Health
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Thing Explainer: Complicated Stuff in Simple Words
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Introduction to Quantum Mechanics
Darrell F. Schroeter, David J. Griffiths
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Factfulness: Ten Reasons We're Wrong About the World--and Why Things Are Better Than You Think
Ola Rosling, Anna Rosling Rönnlund, Hans Rosling
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Universe: The Definitive Visual Guide
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
Entangled Life: How Fungi Make Our Worlds, Change Our Minds and Shape Our Futures
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
How Far the Light Reaches: A Life in Ten Sea Creatures
-30% ar kodu BOOKS
Piegādātāja noliktavā
TOP
The Light Eaters: How the Unseen World of Plant Intelligence Offers a New Understanding of Life on Earth
-30% ar kodu BOOKS
Piegādātāja noliktavā
Aprašymas
This volume of Methods in Molecular Biology focuses on techniques to determine the function of a gene. Traditionally, the function of a gene was determined following cloning, which provided its DNA sequence and an ab- ity to modify this sequence. Experiments were performed that looked for p- notypic changes in a cell line or model organism following modifications to the sequence, knocking out of the gene, or enhancing expression of the gene. In the 1990¿s, the growing sequence databases and the BLAST algorithm provided additional power by allowing identification of genes with known function that had similar sequences and potentially similar molecular mechanisms. On the experimental side, methods, such as two-hybrid screening that could directly determine the partners of specific proteins and even the domains of interaction, came into widespread use. With the advent of high-throughput technologies following completion of the human genome project and similar projects in model organisms, the n- ber of genes of interest has expanded and the traditional methods for gene fu- tion analysis cannot achieve the throughput necessary for large-scale exploration. Although computational tools such as BLAST remain a good point of departure, it is often the case that a gene that appears interesting in a hi- throughput experiment shows no obvious similarity to a gene of known fu- tion. In addition, when BLAST does find a similar gene, the process has often only begun.
Vairāk informācijas
| Izdevējs | Humana Press |
|---|---|
| Series | Methods in Molecular Biology |
| Izlaides gads | 2007 |
| Vāka tips | Cietais vāks |
| EAN | 9781588297341 |